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» neurodegeneration and microbiology

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image: Bacterial Conduit

Bacterial Conduit

By | May 1, 2013

Desulfobulbaceae bacteria were recently discovered to form centimeter-long cables, containing thousands of cells that share an outer membrane.

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image: Electron Shuffle

Electron Shuffle

By | May 1, 2013

Shewanella bacteria generate energy for survival by transporting electrons to nearby mineral surfaces.

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image: Antibody-Dependent Enhanced (ADE) Immunity

Antibody-Dependent Enhanced (ADE) Immunity

By | March 2, 2013

The method to the dengue virus's maddening infectiousness.

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image: The Soil Microbiome

The Soil Microbiome

By | January 1, 2013

There's a lot more than dirt to the soil in which plants grow.

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image: Lost in Space

Lost in Space

By | September 1, 2011

Looking for a more realistic way to study memory, we turned to place cells­­—­a network of cells that record a rat’s memory of an environment. 

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image: Molecular Learning

Molecular Learning

By | September 1, 2011

Long-term potentiation (LTP), discovered in the 1970s, was later shown to be the molecular basis of memory. 

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image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to the aging process.

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

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image: Harmful Bacterial Metabolites

Harmful Bacterial Metabolites

By | August 1, 2011

Gut bacteria that feed on healthy food appear to amplify the nutritional benefits of those foods. However, they also appear to amplify the undesirable effects of unhealthy food. 

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image: Intestinal Molecular Signaling

Intestinal Molecular Signaling

By | January 1, 2011

Microbes, both good and bad, can exert direct effects on host cells and vice versa. 

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