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» neurodegeneration, neuroscience and cancer

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image: Neurogenesis in the Mammalian Brain

Neurogenesis in the Mammalian Brain

By | October 1, 2015

Neuron nurseries in the adult brains of rodents and humans appear to influence cognitive function.

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image: Sex on the Brain

Sex on the Brain

By | October 1, 2015

Masculinization of the developing rodent brain leads to significant structural differences between the two sexes.

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image: Closing the Loop

Closing the Loop

By | October 1, 2015

Micromanaging neuronal behavior with optogenetics

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image: Sugar Coma Model

Sugar Coma Model

By | October 1, 2015

How glucose fires up sleep-inducing neurons

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image: Mapping Corti

Mapping Corti

By | September 3, 2015

The inner ear organ, from macro to micro

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image: Insulin's Role in Body and Brain

Insulin's Role in Body and Brain

By , and | December 6, 2012

Insulin, long recognized as a primary regulator of blood glucose, is now also understood to play key roles in neuroplasticity, neuromodulation, and neurotrophism.

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image: Telomere Basics

Telomere Basics

By | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. 

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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

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image: Suspected Effects of Vitamin D

Suspected Effects of Vitamin D

By | March 1, 2012

Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. 

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image: Inflammation, Pain, and Resolvins

Inflammation, Pain, and Resolvins

By | January 1, 2012

Not all inflammation leads to pain. Despite widespread infection followed by fever, colds rarely cause pain. But when some cytokines and certain immune cells are active near pain-sensing nerves, they trigger receptors that convey pain sensations to the brain.

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