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Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
RNAs
Drug Discovery Techniques Open the Door to RNA-targeted Drugs
Amber Dance | Jun 1, 2019 | 8 min read
New ways to search for druggable RNAs and matching small molecules
An image of lung tissue acquired using a MALDI imaging mass spectrometer.
Glycogen Metabolism May Play a Key Role in Pulmonary Fibrosis
Charlene Lancaster, PhD | Sep 11, 2023 | 4 min read
Researchers discover that glycogen and N-linked glycans accumulate in fibrotic regions of the lung and may be important for therapy development.
Cancer cell
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.
Photo of Ankara Jain in his lab
Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease
Hannah Thomasy, PhD | Oct 3, 2022 | 3 min read
The MIT biologist studies how RNA molecules self-assemble and the role these accumulations may play in diseases such as ALS and Huntington’s.
Drugging the Disorderome
Amber Dance | Oct 1, 2017 | 8 min read
Strategies for targeting intrinsically disordered proteins
Next Generation: Cancer Drug in Disguise
Kate Yandell | Nov 5, 2013 | 3 min read
Researchers develop a strategy for rendering a toxic drug harmless—until it encounters a pair of enzymes that signals cancer cells are nearby.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

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