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tag cancer neuroscience drug development genetics genomics
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Rodents Offer New Insights Into the Diversity of Addiction
Aparna Nathan, PhD
| Dec 1, 2023
| 4 min read
Molecular studies may point to underlying genetics and therapeutic targets.
Novelty Activates a Long Noncoding RNA for Spatial Learning in Mice
Shelby Bradford, PhD
| Feb 6, 2024
| 4 min read
Genes activated in new environments include those used during development.
Silencing Epigenetic Complexes Re-sensitizes Drug-Resistant Cancer Cells
Rachael Moeller Gorman
| Sep 25, 2023
| 4 min read
Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD
| Jan 18, 2024
| 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Exploring the Past, Present, and Future of Brain Organoids
Niki Spahich, PhD
| Feb 18, 2024
| 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Ancient Viral DNA Plays a Role in Human Disease and Development
Aidan Burn,
The Conversation
| Oct 19, 2022
| 4 min read
Viral remnants make up 8 percent of the human genome, and a new study finds that these sequences are still active in healthy people.
Cancers Protect Themselves Against Their Own Mutations
Ida Emilie Steinmark, PhD
| Aug 1, 2023
| 2 min read
Tumors overexpress certain genes to survive a growing pile of harmful mutations, a trait that scientists could exploit to target with drugs.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD
| Mar 15, 2024
| 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
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