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tag cancer physiology neurodegeneration metabolism

Keeping Kidneys Healthy with a Hand from AI
Aparna Nathan, PhD | Dec 11, 2023 | 3 min read
Researchers found new mechanisms and drug targets for cystinosis.
Close-up of wild sea otter (Enhydra lutris) eating shellfish while floating on it's back.
Sea Otters Demonstrate that There Is More to Muscle than Just Movement—It Can Also Bring the Heat
Traver Wright, Melinda Sheffield-Moore, and Randall Davis | Dec 13, 2021 | 4 min read
Sea otters are born with a supercharged metabolism that helps them stay warm in chilly waters.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
Photo of Ankara Jain in his lab
Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease
Hannah Thomasy, PhD | Oct 3, 2022 | 3 min read
The MIT biologist studies how RNA molecules self-assemble and the role these accumulations may play in diseases such as ALS and Huntington’s.
Micrograph of kidney tissue from a mouse
Vesicles from Young Mice Alleviate Signs of Aging in Older Animals
Catherine Offord | Oct 19, 2022 | 4 min read
Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.
Cancer Diet Shared by Healthy Cells
Beth Marie Mole | Jan 23, 2013 | 3 min read
Tumor cells rapidly divide by usurping a metabolic trick from normal cell development.
DNA Damage Responses: Cancer and Beyond
Michael Kastan(michael.kastan@stjude.org) | Oct 9, 2005 | 5 min read
The composition and sequence of 3 billion bases of DNA serve as a major determinant of our individual physiology.
Power Failure
Megan Scudellari | May 1, 2011 | 10+ min read
Does mitochondrial dysfunction lie at the heart of common, complex diseases like cancer and autism?
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
How Exercise Reprograms the Brain
Ashley Yeager | Nov 1, 2018 | 10 min read
As researchers unravel the molecular machinery that links exercise and cognition, working out is emerging as a promising neurotherapy.

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