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image: A Complex Disorder

A Complex Disorder

By , and | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  


image: Not Immune to Fat

Not Immune to Fat

By | November 1, 2015

The effect of a high-fat diet on murine T cells


image: Going Viral

Going Viral

By | September 1, 2013

Bacteriophages shuttle genes between diverse ecosystems.

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image: Networking Medicine

Networking Medicine

By | March 2, 2013

Although fully organized patient-run trials are still few and far between, patients are taking a more active role in clinical research.


image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role


image: Delivering New Genes

Delivering New Genes

By | June 1, 2012

Gene therapies typically involve the introduction of genetic material into target cells to replace or supplement an existing, usually dysfunctional, gene. 


image: Digging the Underground Life

Digging the Underground Life

By | June 1, 2012

A rare peek inside the subterranean home of the naked mole-rat


image: Messing with HIV

Messing with HIV

By | June 1, 2012

Sangamo Biosciences is putting a different spin on gene therapy. 


image: Telomere Basics

Telomere Basics

By | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. 


image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 


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