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Infographic showing how CITE-seq detects protein and gene expression in the same cell
Infographic: Capturing a More Complete Picture of Expression
CITE-seq draws upon the unbiased nature of single-cell RNA sequencing to gather new insights about protein and gene expression within the same cell.
Infographic: Capturing a More Complete Picture of Expression
Infographic: Capturing a More Complete Picture of Expression

CITE-seq draws upon the unbiased nature of single-cell RNA sequencing to gather new insights about protein and gene expression within the same cell.

CITE-seq draws upon the unbiased nature of single-cell RNA sequencing to gather new insights about protein and gene expression within the same cell.

inflammation, neuroscience

3D image of a neuron cell network with a red glow representing inflammation.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
Human brain stock photo
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment
Deanna MacNeil, PhD | Jan 23, 2023 | 3 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
The fight against time
The Scientist Speaks - The Fight Against Time: Stem Cells and Healthy Aging 
The Scientist | 2 min read
Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline. 
A man working at a computer late at night
Shift Work Early in Life Results in Increased Stroke Severity in Middle Age
Jennifer Zieba, PhD | Jan 11, 2023 | 3 min read
Researchers found that shifted sleep/wake cycles in young rats result in increased functional deficits and mortality following stroke later in life.
Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Laura Dattaro, Spectrum | Jan 11, 2023 | 4 min read
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
Central Nervous System Modeling with iPSC-Derived Cells
The Creative Services Team in collaboration with BrainXell | 1 min read
Bryan Black and Lucas Thal will discuss their experiences screening hiPSC-derived neural cells to understand chronic pain and neuroinflammation.
mice on wheel and ground
Exercise-Associated Protein Boosts Brain Function in Mice
Chloe Tenn | Dec 9, 2021 | 5 min read
A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.
A multicolored section of a fruit fly brain
Tumors Disrupt the Blood-Brain Barrier at a Distance
Abby Olena, PhD | Sep 9, 2021 | 4 min read
Shoring up the tissues that separate neurons and other brain cells from the circulatory system in fruit flies and mice can prolong life in the presence of a tumor.
Breaking Down Barriers
The Scientist | 1 min read
Looking at the future of neurodegeneration research!
illustration of a blue neuron lit with red
Neuron-Released Protein Can Set Off Inflammation: Study
Marcus A. Banks | Aug 19, 2021 | 3 min read
Research in mice suggests that moderating nerve activity with drugs or electrical pulses could modify tissue immune responses, curtailing the chronic pain often associated with inflammatory conditions.
A close-up of a fruit fly head with antenna clearly visible in front of its red eyes
Bacterial Infections Disrupt Flies’ Sense of Smell
Abby Olena, PhD | Jul 21, 2021 | 4 min read
The temporary loss of olfaction stops the flies from eating any more of whatever it is that made them sick.
A Tweak to Immune Cells Reverses Aging in Mice
Abby Olena, PhD | Jan 20, 2021 | 3 min read
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
Study Points to Novel Role for Microglia in Down Syndrome
Catherine Offord | Oct 6, 2020 | 4 min read
Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.
Lost Smell and Taste Hint COVID-19 Can Target the Nervous System
Ashley Yeager | Mar 24, 2020 | 5 min read
The symptoms suggest SARS-CoV-2 might infect neurons, raising questions about whether there could be effects on the brain that play a role in patients’ deaths, but the data are preliminary.
Infographic: The Neurobiology of Suicidal Behavior
Catherine Offord | Jan 13, 2020 | 2 min read
Clues about the biological mechanisms that contribute to a person’s chance of contemplating or attempting suicide
What Neurobiology Can Tell Us About Suicide
Catherine Offord | Jan 13, 2020 | 10+ min read
The biochemical mechanisms in the brain underlying suicidal behavior are beginning to come to light, and researchers hope they could one day lead to better treatment and prevention strategies.
Scientists Criticize Mouse Study of New Alzheimer’s Drug
Emily Makowski | Nov 13, 2019 | 3 min read
Oligomannate, recently approved in China, is being met with some skepticism from researchers.
Glial Ties to Persistent Pain
Mark R. Hutchinson | Jan 1, 2018 | 10 min read
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
Infographic: Two Pain Paths Diverge in the Body
Mark R. Hutchinson | Dec 31, 2017 | 2 min read
The acute pain that results from injury or disease is very different from chronic pain.
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