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image: A Complex Disorder

A Complex Disorder

By , and | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  


image: Not Immune to Fat

Not Immune to Fat

By | November 1, 2015

The effect of a high-fat diet on murine T cells


image: Antibody-Dependent Enhanced (ADE) Immunity

Antibody-Dependent Enhanced (ADE) Immunity

By | March 2, 2013

The method to the dengue virus's maddening infectiousness.


image: Rhinoviruses Exposed

Rhinoviruses Exposed

By | February 1, 2013

Some of these insidious viruses expertly subvert the host immune system, allowing their unhindered proliferation.


image: Adipose Tissue Metabolism in the Obese

Adipose Tissue Metabolism in the Obese

By | December 12, 2012

Fat cells behave differently in obese individuals, causing inflammation and insulin resitance.

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image: Normal Fat Tissue Metabolism

Normal Fat Tissue Metabolism

By | December 6, 2012

Adipose tissue plays an immune role in individuals of normal wieght.


image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role


image: Ubiquitin basics

Ubiquitin basics

By | July 1, 2012

Despite its discovery as a protein that seems to show up everywhere, at least in eukaryotic cells, researchers are only beginning to scratch the surface of all of the cellular functions involving ubiquitin. 


image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 


image: How Drugs Interact with a Baby’s Parts

How Drugs Interact with a Baby’s Parts

By | March 1, 2012

A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve


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