» inflammation, biochemistry, immunology and cancer

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image: A Complex Disorder

A Complex Disorder

By , and | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  


image: Not Immune to Fat

Not Immune to Fat

By | November 1, 2015

The effect of a high-fat diet on murine T cells


image: Antibody-Dependent Enhanced (ADE) Immunity

Antibody-Dependent Enhanced (ADE) Immunity

By | March 2, 2013

The method to the dengue virus's maddening infectiousness.


image: Rhinoviruses Exposed

Rhinoviruses Exposed

By | February 1, 2013

Some of these insidious viruses expertly subvert the host immune system, allowing their unhindered proliferation.


image: Adipose Tissue Metabolism in the Obese

Adipose Tissue Metabolism in the Obese

By | December 12, 2012

Fat cells behave differently in obese individuals, causing inflammation and insulin resitance.

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image: Normal Fat Tissue Metabolism

Normal Fat Tissue Metabolism

By | December 6, 2012

Adipose tissue plays an immune role in individuals of normal wieght.


image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role


image: Ubiquitin basics

Ubiquitin basics

By | July 1, 2012

Despite its discovery as a protein that seems to show up everywhere, at least in eukaryotic cells, researchers are only beginning to scratch the surface of all of the cellular functions involving ubiquitin. 


image: Telomere Basics

Telomere Basics

By | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. 


image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 


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