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» drug development, cancer and neuroscience

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image: Neurogenesis in the Mammalian Brain

Neurogenesis in the Mammalian Brain

By | October 1, 2015

Neuron nurseries in the adult brains of rodents and humans appear to influence cognitive function.

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image: Sex on the Brain

Sex on the Brain

By | October 1, 2015

Masculinization of the developing rodent brain leads to significant structural differences between the two sexes.

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image: Closing the Loop

Closing the Loop

By | October 1, 2015

Micromanaging neuronal behavior with optogenetics

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image: Sugar Coma Model

Sugar Coma Model

By | October 1, 2015

How glucose fires up sleep-inducing neurons

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image: Mapping Corti

Mapping Corti

By | September 3, 2015

The inner ear organ, from macro to micro

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image: Insulin's Role in Body and Brain

Insulin's Role in Body and Brain

By , and | December 6, 2012

Insulin, long recognized as a primary regulator of blood glucose, is now also understood to play key roles in neuroplasticity, neuromodulation, and neurotrophism.

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image: Delivering New Genes

Delivering New Genes

By | June 1, 2012

Gene therapies typically involve the introduction of genetic material into target cells to replace or supplement an existing, usually dysfunctional, gene. 

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image: Telomere Basics

Telomere Basics

By | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. 

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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

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image: How Drugs Interact with a Baby’s Parts

How Drugs Interact with a Baby’s Parts

By | March 1, 2012

A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve

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