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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

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image: Helpful Bacterial Metabolites

Helpful Bacterial Metabolites

By | August 1, 2011

While gut microbiota appear to have both positive and negative impacts on our  health, in the guts of healthy, lean individuals, the good outweighs the bad.  

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image: From the Ground Up

From the Ground Up

By | August 1, 2011

As the planet warms plant growth will likely increase—locking up some of that extra carbon dioxide by converting it into vegetative biomass—but that’s not the whole story. 

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image: Harmful Bacterial Metabolites

Harmful Bacterial Metabolites

By | August 1, 2011

Gut bacteria that feed on healthy food appear to amplify the nutritional benefits of those foods. However, they also appear to amplify the undesirable effects of unhealthy food. 

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image: Cell-In-Cell Action

Cell-In-Cell Action

By | August 1, 2011

The mechanism by which tumor cells end up harboring other living cells remains elusive, and the sparse evidence acquired thus far has led researchers to propose different hypotheses. 

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image: OPSINS: Tools of the trade

OPSINS: Tools of the trade

By | July 1, 2011

The optogenetic toolset is composed of genetically encoded molecules that, when targeted to specific neurons in the brain, enable the electrical activity of those neurons to be driven or silenced by light. 

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image: Exosome Basics

Exosome Basics

By | July 1, 2011

Exosomes are small membrane vesicles secreted by most cell types. Internal vesicles form by the inward budding of cellular compartments known as multivesicular endosomes (MVE). 

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image: Smashing Crystals

Smashing Crystals

July 1, 2011

A powerful new X-ray–generating laser is imaging smaller crystals than ever before.

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image: The Anatomy of a High

The Anatomy of a High

By | June 3, 2011

When someone snorts or smokes cocaine, which is composed of small crystalline alkaloid molecules, the drug enters the bloodstream and from there eventually crosses into the heart, brain, and other organs. 

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image: Part Human, Part HIV

Part Human, Part HIV

By | June 3, 2011

Like other enveloped viruses, HIV exits its host cell enshrouded in the cell’s membrane, which contains membrane molecules such as the human leukocyte antigens (HLA). 

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    For decades, the only remedies for hearing loss were devices such as hearing aids or cochlear implants. Now, the first pharmaceutical treatments may be on the way.
     

  3. Psychology’s Failure to Replicate
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    Features The Great Big Clean-Up

    From tossing out cross-contaminated cell lines to flagging genomic misnomers, a push is on to tidy up biomedical research.

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