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» physiology, disease/medicine and cancer

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image: How Drugs Interact with a Baby’s Parts

How Drugs Interact with a Baby’s Parts

By | March 1, 2012

A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve

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image: Suspected Effects of Vitamin D

Suspected Effects of Vitamin D

By | March 1, 2012

Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. 

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image: Calcium and the Pancreas

Calcium and the Pancreas

By | February 1, 2012

Normal pancreatic function depends on the precise flow of calcium within and into the acinar cells of the organ. 

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image: Swallowing the Surgeon

Swallowing the Surgeon

By | October 1, 2011

In fewer than 15 years, nanomedicine has gone from fantasy to reality.

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image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to the aging process.

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

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image: Helpful Bacterial Metabolites

Helpful Bacterial Metabolites

By | August 1, 2011

While gut microbiota appear to have both positive and negative impacts on our  health, in the guts of healthy, lean individuals, the good outweighs the bad.  

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image: Harmful Bacterial Metabolites

Harmful Bacterial Metabolites

By | August 1, 2011

Gut bacteria that feed on healthy food appear to amplify the nutritional benefits of those foods. However, they also appear to amplify the undesirable effects of unhealthy food. 

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image: Part Human, Part HIV

Part Human, Part HIV

By | June 3, 2011

Like other enveloped viruses, HIV exits its host cell enshrouded in the cell’s membrane, which contains membrane molecules such as the human leukocyte antigens (HLA). 

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image: Where Cancer and Inflammation Intersect

Where Cancer and Inflammation Intersect

By | April 1, 2011

Recent clinical trials have reignited the interest in simple anti-inflammatory drugs like aspirin for controlling the inflammation associated with cancer. 

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