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tag physiology drug development biochemistry neuroscience

A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
3D image of a neuron cell network with a red glow representing inflammation.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
white mouse on wheel
Putative Exercise Hormone Irisin Boosts Mouse Brainpower
Sophie Fessl, PhD | Sep 10, 2021 | 4 min read
Mice lacking irisin didn’t exhibit the cognition improvements that typically follow exercise, and in mouse models of Alzheimer’s disease, treatment with the hormone reduced cognitive decline.
Special Report: Tools For Neuroscience's Third Decade
Laurel Joyce | Oct 28, 1990 | 10+ min read
Neuroscientists are entering the federally designated "Decade of the Brain" armed with a toolbox bulging with new instruments and techniques. Many have been borrowed from other disciplines; others have been specifically designed to probe the secrets of the nervous system. The variety of tools available reflects the diversity of the researchers who consider themselves neuroscientists. "Neuroscience represents a fusion of several scientific disciplines--biophysics, biochemistry, physiology, anat
Antidepressant Approvals Could Herald New Era in Psychiatric Drugs
Bianca Nogrady | Oct 1, 2019 | 9 min read
The FDA has given the green light to the first major new classes of antidepressant therapies in decades, opening up new avenues for therapeutic development.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Muscle Master: Angela Dulhunty
Anna Azvolinsky | Sep 1, 2018 | 9 min read
Having pioneered the study of muscle physiology in mammals, she uncovered how ion channels enable muscle movement.
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020 | 10+ min read
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.

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