inflammation, cell & molecular biology

Research in animals and people supports a range of mechanisms by which the parasites affect physiology and immune responses.

The cholesterol-lowering drugs quell inflammation and reverse endothelial tissue damage, hints that they might curb the body’s excessive immune response to SARS-CoV-2 infection.

The symptoms suggest SARS-CoV-2 might infect neurons, raising questions about whether there could be effects on the brain that play a role in patients’ deaths, but the data are preliminary.

The findings could represent a novel mechanism for relieving inflammatory pain.

Normal hair growth can lead to infection during cancer treatment.

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

The acute pain that results from injury or disease is very different from chronic pain.

Viruses within Salmonella rapidly spread genes throughout the bacterial population during a gut infection, scientists show.

NSAIDs reduce this "parainflammation," hinting at how they help lower cancer risk.

Obesity triggers a fatty acid synthesis pathway, which in turn helps drive T cell differentiation and inflammation.

Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?

The effect of a high-fat diet on murine T cells

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.
 

The activity of one type of immune cell helps regrow the limbs of amputated salamanders.

Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role

A roundup of recent research announced this week at the annual conference of the American Association for Cancer Research (AACR).

Early experiments show that a hybrid form of the common pain reliever can effectively inhibit the growth of many tumor types.

The Nobel Assembly announced today that three researchers in the field of immunology will share the 2011 Prize in Physiology or Medicine.