Most Recent

image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to the aging process.


image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.


image: Helpful Bacterial Metabolites

Helpful Bacterial Metabolites

By | August 1, 2011

While gut microbiota appear to have both positive and negative impacts on our  health, in the guts of healthy, lean individuals, the good outweighs the bad.  


image: Harmful Bacterial Metabolites

Harmful Bacterial Metabolites

By | August 1, 2011

Gut bacteria that feed on healthy food appear to amplify the nutritional benefits of those foods. However, they also appear to amplify the undesirable effects of unhealthy food. 


image: Exosome Basics

Exosome Basics

By | July 1, 2011

Exosomes are small membrane vesicles secreted by most cell types. Internal vesicles form by the inward budding of cellular compartments known as multivesicular endosomes (MVE). 


image: Where Cancer and Inflammation Intersect

Where Cancer and Inflammation Intersect

By | April 1, 2011

Recent clinical trials have reignited the interest in simple anti-inflammatory drugs like aspirin for controlling the inflammation associated with cancer. 


image: Epigenetics—A Primer

Epigenetics—A Primer

By | March 1, 2011

Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin. 


image: Stress and Inflammation

Stress and Inflammation

By | February 1, 2011

Stress and inflammation Cardiovascular disease, including coronary artery disease and stroke, is the single greatest cause of death worldwide and is a major burden on health services and society. 



Popular Now

  1. Sex Differences in the Brain
    Features Sex Differences in the Brain

    How male and female brains diverge is a hotly debated topic, but the study of model organisms points to differences that cannot be ignored.

  2. Brain Gain
    Features Brain Gain

    Young neurons in the adult human brain are likely critical to its function.

  3. DNA Repair Pioneers Win Nobel
    Daily News DNA Repair Pioneers Win Nobel

    Tomas Lindahl, Paul Modrich, and Aziz Sancar have won this year’s Nobel Prize in Chemistry for their work elucidating mechanisms of DNA repair.

  4. Antiparasite Drug Developers Win Nobel
    Daily News Antiparasite Drug Developers Win Nobel

    William Campbell, Satoshi Omura, and Youyou Tu have won this year’s Nobel Prize in Physiology or Medicine in recognition of their contributions to antiparasitic drug development.

Life Technologies