cell & molecular biology, drug development

SARS-CoV-2, the virus that causes COVID-19, taps into human proteases such as furin to enter cells. Temporarily inhibiting those enzymes might stymie infection.

In two independent studies, researchers find that the organelle is responsible for a switch that allows cells to start moving when they’re squeezed.

The DNA-protein complex has branches that fold back on themselves.

A growth factor treatment helps improve cardiac functioning after heart attack in pigs.

The physician-researcher laid the groundwork for genetic cloning and led the US Food and Drug Administration as the country faced the AIDS crisis in the 1980s.

Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.

Scientists are devising human-animal hybrids for harvesting human organs, but lab-derived mini-organs are a less ethically fraught solution to meeting the need for transplantation.

Five independent groups got different results in a drug-response experiment, despite sharing protocols, reagents, and cell lines. The researchers identify technical variables that could be to blame.

An online video game helps researchers create strategies for creating RNA.

Immune functions in the mouse intestine differ by segment.

Researchers create a 3-D printed, portable centrifuge that can be affordably produced for science classrooms.

New ways to search for druggable RNAs and matching small molecules

From the remarkable speed of enzyme-catalyzed reactions to the workings of the human brain, numerous biological puzzles are now being explored for evidence of quantum effects.

Telomeres in cancer cells exposed to oxidative stress got shorter and stickier.

Scientists create an atlas of Arabidopsis cell and tissue reconstructions in three dimensions.

With genetic tweaks, researchers can coax corn and other cereals to take in more iron, but sometimes the plants rebel.

The recent discovery of 17 people who have inherited maternal and paternal lines of mitochondrial DNA has major ramifications for medical and ancestry research.

Shapiro helped to found the field of systems biology.