cell & molecular biology, drug development

The miniscule carriers successfully transported and released live cells at a particular location within living mice.

A new technique could allow researchers to better understand bacteria-host interactions over the course of an infection.

The race to develop analgesic drugs that inhibit sodium channel Na_V1.7 is revealing a complex sensory role for the protein.

Since the mid-2000s, the voltage-gated sodium channel Na_V1.7 has emerged as a promising target for a new class of analgesics.

New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

And the same endocannabinoid system that translates marijuana's buzz-inducing compounds into a high plays crucial roles in health and disease outside the brain.

The structure and function of the cell's protein-degrading machine

Across many diseases, taking medication at specific times of day may make the therapy more effective.

Scientists identify the genes responsible for bacteria-controlled sterility in arthropods.

A study provides the first visual evidence that cytofilaments tunnel through a cell’s nucleus to the extracellular matrix.

This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.

A clever twist on a super-resolution microscopy technique improves the temporal resolution of single-molecule tracking. 

Knowing where our bodies are in space is critical for the control of our movements and for our sense of self.

Structural studies reveal how SSRI drugs bind to the human serotonin transporter.

Scientists still don’t know why animals sleep or how to define the ubiquitous behavior.

Associate Professor, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder. Age: 43

Contrary to years of research suggesting otherwise, most aggregated proteins regain their shape and functionality following heat shock.

Physical therapy and exercise are critical to the success of cell therapies approaching the clinic.