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image: Digging the Underground Life

Digging the Underground Life

By | June 1, 2012

A rare peek inside the subterranean home of the naked mole-rat

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image: Messing with HIV

Messing with HIV

By | June 1, 2012

Sangamo Biosciences is putting a different spin on gene therapy. 

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image: Telomere Basics

Telomere Basics

By | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. 

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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

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image: How Drugs Interact with a Baby’s Parts

How Drugs Interact with a Baby’s Parts

By | March 1, 2012

A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve

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image: Suspected Effects of Vitamin D

Suspected Effects of Vitamin D

By | March 1, 2012

Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. 

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image: Calcium and the Pancreas

Calcium and the Pancreas

By | February 1, 2012

Normal pancreatic function depends on the precise flow of calcium within and into the acinar cells of the organ. 

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image: How Autophagy Works

How Autophagy Works

By | February 1, 2012

There are five steps of autophagosome biogenesis: induction, expansion, vesicle completion, fusion, and cargo degradation. 

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image: Taste in the Mouth, Gut, and Airways

Taste in the Mouth, Gut, and Airways

By | December 1, 2011

The tongue may be the epicenter of taste sensation, but taste receptors are scattered throughout the digestive and respiratory tracts.

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image: Swallowing the Surgeon

Swallowing the Surgeon

By | October 1, 2011

In fewer than 15 years, nanomedicine has gone from fantasy to reality.

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