Cover Story

» DNA methylation, immunology and cancer

Most Recent

image: My Mighty Mouse

My Mighty Mouse

By | April 1, 2015

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

1 Comment

image: Viral Virtuosos

Viral Virtuosos

By | February 1, 2015

New understanding of noncoding RNAs may solve a long-standing puzzle about how viruses orchestrate lifelong infections.  


image: Deploying the Body’s Army

Deploying the Body’s Army

By | April 1, 2014

Using patients’ own immune systems to fight cancer


image: Models of Transparency

Models of Transparency

By , , and | April 1, 2013

Researchers are taking advantage of small, transparent zebrafish embryos and larvae—and a special strain of see-through adults—to understand the development and spread of cancer.


image: Fat's Immune Sentinels

Fat's Immune Sentinels

By | December 1, 2012

Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.


image: Lamarck and the Missing Lnc

Lamarck and the Missing Lnc

By | October 1, 2012

Epigenetic changes accrued over an organism’s lifetime may leave a permanent heritable mark on the genome, through the help of long noncoding RNAs.



By | June 1, 2011

Looking back, looking ahead


image: Taking Aim at Melanoma

Taking Aim at Melanoma

By | April 1, 2011

Understanding oncogenesis at the molecular level offers the prospect of tailoring treatments much more precisely for patients with advanced cases of this deadliest of skin cancers.


image: Epigenetic Changes in Cancer

Epigenetic Changes in Cancer

By | March 1, 2011

The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.



Popular Now

  1. Sex Differences in the Brain
    Features Sex Differences in the Brain

    How male and female brains diverge is a hotly debated topic, but the study of model organisms points to differences that cannot be ignored.

  2. Brain Gain
    Features Brain Gain

    Young neurons in the adult human brain are likely critical to its function.

  3. DNA Repair Pioneers Win Nobel
    Daily News DNA Repair Pioneers Win Nobel

    Tomas Lindahl, Paul Modrich, and Aziz Sancar have won this year’s Nobel Prize in Chemistry for their work elucidating mechanisms of DNA repair.

  4. Antiparasite Drug Developers Win Nobel
    Daily News Antiparasite Drug Developers Win Nobel

    William Campbell, Satoshi Omura, and Youyou Tu have won this year’s Nobel Prize in Physiology or Medicine in recognition of their contributions to antiparasitic drug development.

Life Technologies