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tag dna methylation tuberculosis disease medicine

Methylation: Gene Expression at the Right Place and Right Time
Nadia Halim | Dec 5, 1999 | 7 min read
Courtesy of Richard Roberts, New England BiolabsModel methylation reaction: Cytosine nucleotide (red) is flipped out of the DNA double helix by a methyltransferase (white), so it can be methylated. The end product after the methyl group has been transferred to the DNA is pictured in green. A tenuous link between DNA methylation and development has existed for several years. Now findings substantiate the connection. Researchers have found the first human diseases caused by defects in the DNA meth
How Some Vaccines Protect Against More than Their Targets
Shawna Williams | Nov 1, 2020 | 10+ min read
As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.
Stem Cells: Safe Haven For TB
Nsikan Akpan | Feb 5, 2013 | 3 min read
Tuberculosis bacteria find shelter from drugs and the body’s defenses in bone marrow stem cells.
Detecting Tumors from Shed DNA
Douglas Steinberg | May 13, 2001 | 7 min read
Medical institutions across the United States will begin recruiting volunteers next month for a study that its investigators and outside observers describe as groundbreaking. They say it is the first large-scale trial to test the feasibility of using DNA shed by tumors to find early-stage cancer. During the three-year government-funded project, researchers will analyze DNA from stool samples to detect patterns characteristic of colorectal cancer (CRC). The study will have two other notable fe
diabetes complications type 2 biomarker blood test screen hydroxymethylation epigenetics cytosine
Blood-Based Epigenetic Screen Tests for Diabetes Complications
Katarina Zimmer | Oct 1, 2019 | 4 min read
Researchers could accurately detect life-threatening vascular complications in type 2 diabetes patients by analyzing hydroxymethylated cytosines in freely circulating DNA.
Unmasking Secret Identities
Kate Yandell | Feb 1, 2014 | 9 min read
A tour of techniques for measuring DNA hydroxymethylation
Epigenetic Effects of Mom’s Diet
Emily Willingham | Apr 29, 2014 | 3 min read
Molecular markers of a mother’s nutrition around the time of conception can be found in her child’s DNA.
Research Notes
Kate Devine | Sep 17, 2000 | 6 min read
Brain Cells Transplant May Prove Useful as Stroke Treatment About 4 million Americans are survivors of a stroke, the leading cause of adult disability, according to the American Heart Association. Historically, stroke medicine has focused on prevention, immediate treatment, and years of rehabilitation. Now, University of Pittsburgh Medical Center (UPMC) researchers have initiated clinical trials that may ultimately lead to restoration of affected abilities even years after stroke occurrence (D.
Updated July 9
Track COVID-19 Vaccines Advancing Through Clinical Trials
The Scientist | Apr 7, 2020 | 10+ min read
Find the latest updates in this one-stop resource, including efficacy data and side effects of approved shots, as well as progress on new candidates entering human studies.
Bioterrorism Research: New Money, New Anxieties
John Dudley Miller | Apr 6, 2003 | 8 min read
Ned Shaw US scientists have reason to feel both heady and scared. The federal government recently released unprecedented billions of dollars to fund bioterrorism research. Yet, the merits of this sudden shift in focus are being debated, and some worry that the money will be squandered or wasted. "I have been really very upset by the focus on bioterrorism," says Stanley Falkow, professor of microbiology and immunology and of medicine at Stanford University. "Everybody's talking about it, but th

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