vaccine, tuberculosis

More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  

This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.

One hundred years after its invention, BCG has stood the test of time as a vaccine against tuberculosis.

A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.

As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.

Studies are underway to test whether giving a shot of BCG vaccine could protect doctors and nurses against COVID-19.

Tested in patients with the latent form of tuberculosis, the vaccine prevented the development of the active form of infection in 50 percent more individuals compared with unvaccinated patients.

The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.

Research efforts aim to obviate the need for vaccine refrigeration.

Tuberculosis is exquisitely adapted to the human body. Researchers need a new game plan for beating it.

A vaccine developed to ward off tuberculosis may help prevent symptoms of multiple sclerosis, according to a new study.

One of the most advanced tuberculosis vaccines has failed to protect infants from getting the disease in a clinical trial, but it may be effective in adults.

With 12 new tuberculosis vaccines in clinical development, a plan is needed to introduce the most effective ones throughout the world.

Looking back, looking ahead