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image: My Mighty Mouse

My Mighty Mouse

By | April 1, 2015

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

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image: How We Age

How We Age

By | March 1, 2015

From DNA damage to cellular miscommunication, aging is a mysterious and multifarious process.

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image: Deploying the Body’s Army

Deploying the Body’s Army

By | April 1, 2014

Using patients’ own immune systems to fight cancer


image: Models of Transparency

Models of Transparency

By , , and | April 1, 2013

Researchers are taking advantage of small, transparent zebrafish embryos and larvae—and a special strain of see-through adults—to understand the development and spread of cancer.


image: Lamarck and the Missing Lnc

Lamarck and the Missing Lnc

By | October 1, 2012

Epigenetic changes accrued over an organism’s lifetime may leave a permanent heritable mark on the genome, through the help of long noncoding RNAs.



By | June 1, 2011

Looking back, looking ahead


image: Taking Aim at Melanoma

Taking Aim at Melanoma

By | April 1, 2011

Understanding oncogenesis at the molecular level offers the prospect of tailoring treatments much more precisely for patients with advanced cases of this deadliest of skin cancers.


image: Epigenetic Changes in Cancer

Epigenetic Changes in Cancer

By | March 1, 2011

The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.


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