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tag imaging neuroscience e coli

Networking E. coli
David Secko | Mar 1, 2007 | 2 min read
The paper: G. Butland et al., "Interaction network containing conserved and essential protein complexes in Escherichia coli,' Nature, 433:531-7, 2005. (Cited in 91 papers) The finding: Jack Greenblatt and Andrew Emili from the University of Toronto led a team of Canadian researchers that produced a large-scale map of a bacterial interaction network by tagging and purifying protein complexes from 23% of the Escherichia coli genome.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Dethroning E. coli?
Alison F. Takemura | Jun 23, 2016 | 1 min read
Some scientists hope to replace microbiology’s workhorse bacterium with fast-growing Vibrio natriegens.
This image depicts the fruit fly nerve cord connectome. It highlights 930 neurons, a subset of the full set of reconstructed neurons.
The Expansion of Volume Electron Microscopy
Danielle Gerhard, PhD | Sep 8, 2023 | 6 min read
A series of technological advancements for automation and parallel imaging made volume electron microscopy more user friendly while increasing throughput.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Image of the Day: Painting with Viruses
The Scientist and The Scientist Staff | Oct 31, 2017 | 1 min read
Researchers have used a modified rabies virus and fluorescent proteins to tag individual nerve cells in the mouse visual cortex. 
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Image of the Day: CRISPR on a Mouse Canvas
The Scientist and The Scientist Staff | Oct 25, 2017 | 1 min read
Scientists are using CRISPR-Cas9 technology to tag and explore specific sets of neurons in mice, in one of the first steps towards building a comprehensive atlas of brain circuitry. 
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

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