Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Researchers found more than 800 sites in the genome where the twins bore the same chemical tags.

The University of Washington researcher leveraged data from the Human Genome Project to identify genes underlying various health conditions and advance precision medicine.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.

Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

Brian Zambrowicz Now that the human genome has been sequenced to a rough draft, the scientific community is looking down the road to what's next. Last month's announcement (see page 1) spotlights a nascent area of science called functional genomics. Making sense of the sequence in terms of gene function will provide research fodder--and jobs--for the years to come. "Functional genomics is everything after the sequencing studies are finished," remarks Ruben Abagyan, director of computation

A study reveals a connection between the loss of enzymes responsible for removing methyl groups from DNA, nucleic acid knots, and cancer development in mice.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.