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tag science education whole genome sequencing neuroscience

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
A tropical angelfish 
Genome Spotlight: Freshwater Angelfish (Pterophyllum scalare)
Christie Wilcox, PhD | Oct 27, 2022 | 4 min read
A high school student uses crowdfunding to produce the first genome assembly for this popular aquarium species, underscoring the increasing feasibility of whole-genome sequencing.
Whole-Genome SNP Genotyping
Marilee Ogren | Jun 1, 2003 | 8 min read
Clockwise from top left: images courtesy of Affymetrix, Illumina, Sequenom and Illumina Take any two individuals, sequence and compare their genomic DNA, and you'll find that the vast majority (about 99.9%) of the sequences are identical. In the remaining 0.1% lie differences in disease susceptibility, environmental response, and drug metabolism. Researchers are understandably keen to dissect these variations, most of which take the form of single-nucleotide polymorphisms (SNPs). A SNP (pron
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
A C-fern (Ceratopteris richardii) growing in a pot
Genome Spotlight: C-fern (Ceratopteris richardii)
Christie Wilcox, PhD | Sep 22, 2022 | 5 min read
Sequences for the model organism and two of its kin reveal how these plants got their oversized genomes.
An Edith’s checkerspot butterfly
Genome Spotlight: Edith’s Checkerspot Butterfly (Euphydryas editha)
Christie Wilcox, PhD | Aug 25, 2022 | 3 min read
A high-quality genome sequence for this versatile insect will likely aid eco-evolutionary research.
$1,000 Genome at Last?
Tracy Vence | Jan 15, 2014 | 2 min read
Illumina says its newest sequencing system can churn out whole human genomes for $1,000 apiece.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
Sequencing Stakes: Celera Genomics Carves Its Niche
Ricki Lewis | Jul 18, 1999 | 8 min read
J. Craig Venter is no stranger to contradiction and controversy. He seems to thrive on it. In 1991, when the National Institutes of Health was haggling over patenting expressed sequence tags (ESTs)--a shortcut to identifying protein-encoding genes--Venter the inventor accepted a private offer to found The Institute for Genomic Research (TIGR) in Rockville, Md. TIGR would discover ESTs and give most of them to a commercial sibling, Human Genome Sciences (HGS), to market. ESTs are now a standard

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