p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.

Whole genome sequences reveal multiple domestications of this agriculturally important tree and may hold the secrets to producing the sweet fruit year round.

A high school student uses crowdfunding to produce the first genome assembly for this popular aquarium species, underscoring the increasing feasibility of whole-genome sequencing.

A high-quality genome sequence for this versatile insect will likely aid eco-evolutionary research.

Sequences for the model organism and two of its kin reveal how these plants got their oversized genomes.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.

An analysis of the genomes of people from 50 ethnolinguistic groups in Africa spots 62 genes under positive selection and 3 million more genetic variants than previously documented.

J. Craig Venter is no stranger to contradiction and controversy. He seems to thrive on it. In 1991, when the National Institutes of Health was haggling over patenting expressed sequence tags (ESTs)--a shortcut to identifying protein-encoding genes--Venter the inventor accepted a private offer to found The Institute for Genomic Research (TIGR) in Rockville, Md. TIGR would discover ESTs and give most of them to a commercial sibling, Human Genome Sciences (HGS), to market. ESTs are now a standard

An early advocate of the sequencing of the human genome reflects on his own predictions from 1986.