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Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
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What Does It Look Like to “Turn On” a Gene?
Alla Katsnelson, Casey Rentz, and Knowable Magazine | May 3, 2019 | 8 min read
Only recently have scientists directly witnessed this most pivotal of events in biology, thanks to new technology that allows them to observe the process in living cells. It’s teaching them a lot.
Mapping Brain Proteins
Devika G. Bansal | Feb 1, 2018 | 7 min read
Researchers are using souped-up mass spectrometry to localize proteins within brain cells.
Using Mimics to Get Around Antibodies’ Limitations
Devika G. Bansal | Jun 1, 2018 | 7 min read
Synthetic and natural alternatives to traditional antibodies offer more control, specificity, and reproducibility. 
Fascinated by Folding
Anna Azvolinsky | Aug 3, 2017 | 10 min read
Lila Gierasch uses biochemical tools to understand how linear chains of amino acids turn into complex three-dimensional structures.
Antibody Alternatives
Paul Ko Ferrigno and Jane McLeod | Feb 1, 2016 | 10+ min read
Nucleic acid aptamers and protein scaffolds could change the way researchers study biological processes and treat disease.
The Ears Have It
Anna Azvolinsky | Sep 1, 2015 | 8 min read
A teaching obligation in graduate school introduced James Hudspeth to a career focused on how vertebrates sense sounds.
A Vaulted Mystery
Eufemia S. Putortì and Massimo P. Crippa | Aug 1, 2014 | 10+ min read
Nearly 30 years after the discovery of tiny barrel-shape structures called vaults, their natural functions remain elusive. Nevertheless, researchers are beginning to put these nanoparticles to work in biomedicine.
Tricking the Light—Fantastic
Amber Dance | Nov 1, 2010 | 7 min read
Techniques for achieving super-resolution imaging
Start It Up
Dan Cossins | Apr 1, 2013 | 8 min read
Young researchers who left the academic path to transform their bright ideas into thriving companies discuss their experiences, and how you can launch your own business.

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