Cancer News, Articles | The Scientist Magazine®

Crystalline ball-and-stick model representation of a molecular structure.

Prioritizing PARylation in DNA Damage and Repair

The Scientist Staff | Apr 1, 2024 | 2 min read

Measuring cellular poly ADP-ribosylation can unlock new anticancer strategies and approaches.

An image of cells with the center stained green and some cells stained magenta over a black background.

Growing Milk-Secreting Mammary Organoids

Sneha Khedkar | Mar 29, 2024 | 3 min read

Mammary organoids derived from mouse embryonic stem cells could offer clues into mammary gland developmental origins and help researchers study breast cancer.

Tapping into Immunotherapy’s Potential to Help More People

The Scientist Staff | 2 min read

Discover what researchers have learned about varying immunotherapy response rates between patients with the same cancer types.

A single channel splits into two micro-channels.

A Beating Heart on a Chip

Aparna Nathan, PhD | Mar 26, 2024 | 4 min read

Researchers used organ chips to mimic conditions that help heart cells mature.

Image showing monoclonal antibody treatment

The Resilience of Monoclonal Antibodies and their Makers

Laura Tran, PhD | Mar 15, 2024 | 10+ min read

The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.

Defining the Triple Negative Breast Cancer Morpholome

The Scientist Staff | 1 min read

Learn how researchers take a phenotype-first approach to uncover hidden metastatic drivers at tissue and cellular levels.

Infographic: Understanding CAR-T vs TCR Approaches

Danielle Gerhard, PhD | Mar 15, 2024 | 3 min read

Living drugs get a boost from emerging engineering strategies that focus on safety and specificity.

3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor

Next-generation CAR and TCR Cancer Therapies

Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read

From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.

Epigenetic Influences and Mechanisms in Cancer

The Scientist Staff | 1 min read

In this webinar, Özgen Deniz and Christina Leslie will discuss how epigenetic regulation affects oncogenesis.

A needle drawing up fluid from an unlabeled vial.

Cancer Vaccination as a Promising New Treatment Against Tumors

Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read

Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.

Robot hand holding glass sphere with glowing fiber neon communication wires

Gazing into Science’s Crystal Ball

Meenakshi Prabhune, PhD | Mar 15, 2024 | 3 min read

Basic research successes offer glimpses into future scientific advancements, but the outcomes are subject to change.

An Overview of High Throughput Screening

Tanvir Khan, PhD | 5 min read

High throughput screening (HTS) relies on liquid handling devices, robotics, plate readers, and data processing software to automatically test a large number of biological, genetic, chemical, or pharmacological samples.

3D outline of a bone with red dots in the center.

Bringing Immunotherapy Straight to the Source

Aparna Nathan, PhD | Mar 14, 2024 | 4 min read

Engineered natural killer cells track down cancer cells in the bone marrow.

3D illustration of a lymphocyte in white and green.

A Quest for the Holy Grail of Cancer Targets

Danielle Gerhard, PhD | Mar 14, 2024 | 5 min read

Christopher Klebanoff hopes that his search for a small fraction of cancer-specific antigens will have a big impact on cancer cell therapies.

Hijacking Viruses: Optimizing Lentivirus-Based Cell Engineering

The Scientist | 1 min read

Filippo Rossignoli discusses the challenges he faced when employing lentiviruses to produce immunotherapies and how he overcame these obstacles.

A Science Sleuth Accuses a Harvard Medical School Neuroscientist of Research Misconduct

Danielle Gerhard, PhD | Feb 15, 2024 | 5 min read

Researchers await the outcome of an ongoing investigation into dozens of instances of alleged image problems spanning 29 publications over a period of 23 years.

Toppling the Genetic Dominoes in Bone Metastasis

Laura Tran, PhD | Feb 15, 2024 | 4 min read

A key gene that fuels the molecular cascade driving prostate cancer bone metastasis progression may open avenues for targeted therapies.

Precision Medicine: A New Era in Cancer Therapy

Rebecca Roberts, PhD | 6 min read

Precision medicine helps clinicians tailor individual treatments, addressing genetic mutations, tumor microenvironment variations, and therapeutic resistance.