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image: Study Raises Questions About Patient-Derived Xenografts

Study Raises Questions About Patient-Derived Xenografts

By | October 10, 2017

When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.

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image: Image of the Day: Fragile Brain

Image of the Day: Fragile Brain

By | October 3, 2017

In Fragile X syndrome—a genetic mishap that results in cognitive delays—the lack of a translation-repressing protein leads to the rampant accumulation of other proteins in the mouse brain.

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image: How Immune Receptors Got into Mouse Noses

How Immune Receptors Got into Mouse Noses

By | September 1, 2017

A study traces proteins’ evolution from the immune to the olfactory system.

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image: Driving Down Pests

Driving Down Pests

By | August 28, 2017

A computer model estimates that gene-drive technology could wipe out populations of an invasive mammal on islands. 

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image: A Database of Genetic Differences Among Lab Mice

A Database of Genetic Differences Among Lab Mice

By | August 7, 2017

Researchers have catalogued mutations in the coding regions of 36 of the most important mouse strains.

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image: Engineered Human Liver Tissue Grows in Mice

Engineered Human Liver Tissue Grows in Mice

By | July 19, 2017

Tissue “seeds” made up of three cell types and patterned onto a scaffold develop into complex structures with some organ function, researchers show.

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The International Mouse Phenotyping Consortium aims to characterize the entire mouse genome, starting first with more than 3,300 genes. 

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Mouse experiments indicate that, contrary to observations in pregnant women, reactive oxygen species contribute to normal placental development.

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Discrepancies in the populations’ immune systems suggest murine models of immunological disorders possess more limitations than scientists had appreciated.

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image: Upgraded Photoswitch for Vision Repair

Upgraded Photoswitch for Vision Repair

By | April 13, 2017

Researchers improve on a technique to use a light-stimulated small molecule to confer longer-term photosensitivity to the retinal cells of blind mice.

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