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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Yvonne Saenger: Immunotherapy Pioneer

Yvonne Saenger: Immunotherapy Pioneer

By | April 1, 2015

Assistant Professor, Department of Medicine, Columbia University. Age: 41

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image: From Many, One

From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

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image: Resisting Cancer

Resisting Cancer

By | April 1, 2015

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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image: Irisin Skepticism Goes Way Back

Irisin Skepticism Goes Way Back

By | March 18, 2015

Post-publication peer reviewers had questioned data about the supposed fat-browning enzyme from the get-go.

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image: Oldest <em>Homo</em> Remains Yet Found

Oldest Homo Remains Yet Found

By | March 4, 2015

A newly discovered 2.8 million-year-old jawbone is thought to be that of a direct human ancestor.

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image: Capsule Reviews

Capsule Reviews

By | March 1, 2015

Evolving Ourselves, The Man Who Touched His Own Heart, Bats, and The Invaders

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image: Drunk Monkeys

Drunk Monkeys

By | March 1, 2015

UC Berkeley biologist Robert Dudley explains his "drunken monkey" hypothesis for how humans developed a taste for alcohol.

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image: Falling Out of the Family Tree

Falling Out of the Family Tree

By | March 1, 2015

A mutation in an ethanol-metabolizing enzyme arose around the time that arboreal primates shifted to a more terrestrial lifestyle, perhaps as an adaptation to eating fermented fruit.

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