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tag transgenic culture

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Fluorescence microscopy image of cells expressing fluorescent biosensors. Green and magenta fluorescence is observed outside of the cell nuclei.
Choosing Fluorescent Reagents for Every Live Cell Application
The Scientist and MilliporeSigma | Nov 30, 2022 | 4 min read
Scientists gain unique insights into active biological processes with specific fluorescent probes, dyes, and biosensors.
Cancer's Other Conduit
The Scientist Staff | Sep 7, 2003 | 7 min read
Courtesy of Elsevier  DEADLY SPREAD: A: an insulinoma (Ins) in a Rip1Tag2 transgenic mouse. LYVE-1 immunohistochemistry demonstrates the presence of lymphatic vessels in connective tissue, but not near islets of Langerhans. B: Rip1Tag2 mice were crossed with mice which overexpress VEGF-C in pancreatic b-cells. C: An insulinoma cell breaks through a lymphatic vessel. D: An intralymphatic tumor cell mass forms. E: In a lymph node, lymphocytes (L) are surrounded by tumor cells (T). F: Immunof
Capsule Reviews
Annie Gottlieb | Mar 1, 2013 | 3 min read
The Undead, Frankenstein's Cat, The Universe Within, and Physics in Mind
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Phospho-Mania
Aileen Constans | Nov 7, 2004 | 6 min read
ERK1/2 ACTIVATIONCourtesy of Biosource Internationalis plainly visible in heart tissue from an MHC-Rac1 transgenic mouse (right), compared with its normal counterpart (left). Green, pERK 1/2 (pTEpY185/187); blue, actin; red, nuclei.Protein phosphorylation is one of the most widely studied posttranslational modifications, with good reason. Many cellular signaling events rely on the addition or subtraction of phosphate groups (by kinases and phosphatases, respectively) to serine, threonine, and ty
From Buckyballs to Nanotubes
Ricki Lewis | Feb 18, 2001 | 6 min read
Photos © Michael Davidson and The Florida State University These photos show the 60-carbon alkene buckminsterfullerene ("buckyballs"). This substance joins graphite and diamond as a third form of carbon molecule. Technology sometimes derives from clever combinations of tools. Merging immune system cells with cancer cells led to the hybridoma technology that produces monoclonal antibodies. A recipe of restriction enzymes, plasmids, and DNA underlies recombinant DNA and transgenic technologi
How Bacteria Interfere with Insect Reproduction
Ruth Williams | Feb 28, 2017 | 3 min read
Scientists identify the genes responsible for bacteria-controlled sterility in arthropods.
Bacteria Harbor Geometric “Organelles”
Amber Dance | Dec 1, 2018 | 10+ min read
Microbes, traditionally thought to lack organelles, get a metabolic boost from geometric compartments that act as cauldrons for chemical reactions. Bioengineers are eager to harness the compartments for their own purposes.
Blogger Reports STAP Success
Tracy Vence | Apr 1, 2014 | 2 min read
A stem-cell researcher claims to have reproduced stimulus-triggered acquisition of pluripotency by following a revised protocol posted online last week.

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