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image: Soluble Signal

Soluble Signal

By | May 1, 2015

An immune protein previously thought to mark inactive T cells has a free-floating form that correlates with HIV disease progression.

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Defeating the Virus

By | May 1, 2015

Recent discoveries are spurring a renaissance in HIV vaccine research and development.

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image: Protein Spurs T-Cell Proliferation

Protein Spurs T-Cell Proliferation

By | April 17, 2015

A newly discovered protein promotes immunity to viruses and cancer by triggering the production of cytotoxic T cells.

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image: Studying Ebola Survivors

Studying Ebola Survivors

By | April 6, 2015

A scientist jumps at the chance to study the blood of four Ebola survivors to better understand how the immune system responds to the deadly virus. 

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Cancer Immunotherapist

By | April 1, 2015

Scientist to Watch Yvonne Saenger explains recent advances in using biomarkers to identify cancer patients who might benefit most from immunotherapy.

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Control ALT, Delete Cancer

By , , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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