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image: Professional Marksman

Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Yvonne Saenger: Immunotherapy Pioneer

Yvonne Saenger: Immunotherapy Pioneer

By | April 1, 2015

Assistant Professor, Department of Medicine, Columbia University. Age: 41

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image: T Cells of the Skin

T Cells of the Skin

By | March 18, 2015

A census of adaptive immune system components in human skin reveals a variety of resident and traveling memory T cells.

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image: Fighting Allergy with Allergen

Fighting Allergy with Allergen

By | February 25, 2015

Babies who ate peanuts were less likely to develop an allergy to the food by the time they hit kindergarten, according to a new study.

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image: Medical Equipment May Spread Superbug

Medical Equipment May Spread Superbug

By | February 20, 2015

Drug-resistant bacteria have spread in a Los Angeles hospital, perhaps from contaminated endoscopes.

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image: Anticipating Resistance

Anticipating Resistance

By | February 16, 2015

Using computational algorithms and experimental evolution, researchers are predicting antimicrobial-resistance patterns to improve drug design. 

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image: Long-Lived Immunotherapy Stem Cells

Long-Lived Immunotherapy Stem Cells

By | February 4, 2015

Genetically modified T memory stem cells persist in patients for more than 10 years, and can differentiate into a variety of T cell types.

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image: B Cell Bosses

B Cell Bosses

By | February 1, 2015

Gut bacteria in mice spur regulatory B cells to differentiate and release an anti-inflammatory cytokine.

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