The Scientist

» drug resistance and ecology

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image: Professional Marksman

Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.


image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.


image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.


image: Capsule Reviews

Capsule Reviews

By | March 1, 2015

Evolving Ourselves, The Man Who Touched His Own Heart, Bats, and The Invaders

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image: Medical Equipment May Spread Superbug

Medical Equipment May Spread Superbug

By | February 20, 2015

Drug-resistant bacteria have spread in a Los Angeles hospital, perhaps from contaminated endoscopes.

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image: Anticipating Resistance

Anticipating Resistance

By | February 16, 2015

Using computational algorithms and experimental evolution, researchers are predicting antimicrobial-resistance patterns to improve drug design. 


image: Understanding Antimalarial Drug Resistance

Understanding Antimalarial Drug Resistance

By | January 21, 2015

Researchers identify mutations associated with resistance to the frontline antimalarial drug artemisinin.


image: Tracking Tuberculosis Over Time

Tracking Tuberculosis Over Time

By | January 19, 2015

Genomic analysis of a multidrug-resistant lineage pinpoints historical correlations with human events.


image: Taming Bushmeat

Taming Bushmeat

By | January 1, 2015

Chinese farmers’ efforts at rearing wild animals may benefit conservation and reduce human health risks.

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image: Bats Make a Comeback

Bats Make a Comeback

By | December 22, 2014

Citizen-scientist data obtained through the U.K.’s National Bat Monitoring Programme show that populations of 10 bat species have stabilized or are growing.


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