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Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

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The Nobel laureate and Lasker awardee developed tools that facilitated decades of genetics research, including starch gel electrophoresis and gene targeting.

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A team of scientists was unable to replicate controversial, high-profile findings published in 2011.

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image: Those We Lost in 2016

Those We Lost in 2016

By | December 23, 2016

The scientific community bid farewell to several luminaries this year.

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image: Mouse Immunology Paper Retracted

Mouse Immunology Paper Retracted

By | December 16, 2016

A finding of misconduct spurs the retraction of a Science paper claiming to have identified a protein in mice that boosted immunity to both viruses and cancer.

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image: Video: Watch Cells Crawl To Firmer Ground

Video: Watch Cells Crawl To Firmer Ground

By | December 11, 2016

This collective migration, called durotaxis, depends on which cells get the best grip on a surface.

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Scientists present evidence of bacteria-driven mating in flagellate eukaryotes at the American Society for Cell Biology annual meeting.

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image: Controlled Splicing Extends Life Span in Roundworms

Controlled Splicing Extends Life Span in Roundworms

By | December 7, 2016

Increasing the expression of an RNA splicing factor mimics dietary restriction, prolonging life in nematodes. 

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image: “Celldance” Selections

“Celldance” Selections

By | December 5, 2016

Highlights from the American Society for Cell Biology’s 2016 video grant competition

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image: Naive T Cells Find Homes in Lymphoid Tissue

Naive T Cells Find Homes in Lymphoid Tissue

By | December 2, 2016

The human lymph nodes and spleen maintain unique, compartmentalized sets of naive T cells well into old age.

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