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tag conservation biology cell molecular biology microbiology

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Collage of images including sperm, bacteria, coral, and an illustration of a researcher
Our Favorite Cell and Molecular Biology Stories of 2021
Jef Akst | Dec 2, 2021 | 3 min read
Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.
Image of the Day: Cell Droplets
The Scientist and The Scientist Staff | Apr 4, 2018 | 1 min read
Proteins and RNA aggregate into “membraneless organelles” due to liquid-liquid phase separation.
Molecular Biology
The Scientist Staff | Dec 9, 1990 | 1 min read
M. Horikoshi, C.K. Wang, H. Fujii, J.A. Cromlish, et al., "Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box," Nature, 341, 299-303, 28 September 1989. Masami Horikoshi (Rockefeller University, New York): "This paper describes the cloning of the gene encoding the TATA box [a conserved sequence of bases]-binding factor TFIID [transcription factor IID], which we and others have shown to be a key factor in both basic promoter
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Molecular Biology
The Scientist Staff | Jan 20, 1991 | 3 min read
C.K. Glass, S.M. Lipkin, O.V. Devary, M.G. Rosenfeld, "Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer," Cell, 59, 697-708, 17 November 1989. Christopher K. Glass (School of Medicine, University of California, San Diego, La Jolla): "Retinoic acid receptors appear to exert profound effects on vertebrate development by binding to target genes and altering the rates at which they are transcribed in response to retinoic acid. Because t
Molecular Biology
The Scientist Staff | Feb 17, 1991 | 3 min read
R.J. Bandziulis, M.S. Swanson, G. Dreyfuss, "RNA-binding proteins as developmental regulators," Genes and Development, 3, 431-7, April 1989. Gideon Dreyfuss (University of Pennsylvania School of Medicine, Philadelphia): "Protein structural comparisons led to the discovery of identifying and unifying features shared by RNA-binding proteins of the nucleus and cytoplasm. Many of these ribonucleoproteins contain an RNA-binding domain (RBD) of approximately 90 amino acids. This amino acid sequence
Molecular Biology
The Scientist Staff | Feb 20, 1994 | 2 min read
S. Matsuda, H. Kosako, K. Takenaka, K. Moriyama, H. Sakai, T. Akiyama, Y. Gotoh, E. Nishida, "Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade," The EMBO Journal, 11:973-82, 1992. Eisuke Nishida (Department of Genetics and Molecular Biology, Institute for Virus Research, Kyoto University, Japan): "MAP kinases have been described as serine/threonine kinases that are acti
Molecular Biology
The Scientist Staff | Nov 13, 1994 | 2 min read
C.F. Lesser, C. Guthrie,"Mutations in U6 snRNA that alter splice-site specificity--implications for the active site," Science, 262:1982-88, 1993. Cammie Lesser (Department of Biochemistry and Biophysics, School of Medicine, University of California, San Francisco): "Nuclear pre-mRNA splicing is the process by which the introns- -the noncoding portions of precursor mRNAs--are removed and the coding sequences called exons are ligated
Molecular Biology
The Scientist Staff | Nov 13, 1994 | 2 min read
C.F. Lesser, C. Guthrie,"Mutations in U6 snRNA that alter splice-site specificity--implications for the active site," Science, 262:1982-88, 1993. Cammie Lesser (Department of Biochemistry and Biophysics, School of Medicine, University of California, San Francisco): "Nuclear pre-mRNA splicing is the process by which the introns- -the noncoding portions of precursor mRNAs--are removed and the coding sequences called exons are ligated

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