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» aging and immunology

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image: Molecular Learning

Molecular Learning

By | September 1, 2011

Long-term potentiation (LTP), discovered in the 1970s, was later shown to be the molecular basis of memory. 

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image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to the aging process.

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Contributors

September 1, 2011

Meet some of the people featured in the September 2011 issue of The Scientist.

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image: Hold That Thought

Hold That Thought

By | September 1, 2011

In the memory circuits of the aging brain and the signaling pathways of pain, science is trading mystery for mastery.

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image: Piggyback Pathogen

Piggyback Pathogen

By | September 1, 2011

Editor’s Choice in Immunology

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

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image: Blood’s Role in the Aging Brain

Blood’s Role in the Aging Brain

By | August 31, 2011

A blood protein involved in allergy contributes to the decline in brain function and memory in aging mice.

18 Comments

image: Hiding Under a Cap

Hiding Under a Cap

By | August 30, 2011

Editor's Choice in Immunology

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image: The Risk of Aging Fathers

The Risk of Aging Fathers

By | August 30, 2011

Older male mice sired offspring that had more copy number mutations, including several linked to autism and schizophrenia.

15 Comments

image: A Chronic Lyme Biomarker?

A Chronic Lyme Biomarker?

By | August 8, 2011

Researchers identify an antibody profile that may mark patients who suffer persistent symptoms of the tick-borne disease.

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