aging

Analyses of blood from thousands of people show distinct protein profiles are linked to complex diseases of aging.

Despite the treatment being given for only six weeks, the positive effects lasted for a year.

The researchers say that their results are evidence we haven’t yet reached a limit to human lifespan.

A proposed definition of the disease emphasizes signs of neurodegeneration and the presence of β-amyloid and tau, rather than cognitive symptoms.

Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.

The findings suggest that faster synthesis, rather than decreased clearance, causes the protein to build up in neurons.

Two studies examining the effects of parents’ ages on their offsprings’ telomere lengths come to opposite conclusions.  

The findings contradict what has been observed in humans.  

Scientists identified a gene involved in the age-related deterioration of mouse neural stem cells.

From extending lifespan to bolstering the immune system, the drug’s effects are only just beginning to be understood.

Relive the Lasker Award speech from University of Basel biologist Michael Hall.

Researchers find that while bats in the Myotis genus don’t produce telomerase, the enzyme that lengthens telomeres, they possess 21 telomere maintenance–related genes.

Small trials using younger donors and elderly recipients hint that mesenchymal stem cell transfers might reduce frailty. 

A new analysis of Dolly’s skeleton suggests the cloned sheep’s arthritis did not lead to her death. 

Shorter telomere length is widely considered a manifestation of stress in young children, but the results of a new study find it’s more complicated than that.  

Mutations in both copies of SERPINE1 can result in blood clotting disorders, but carriers might enjoy longer lifespan and health benefits. 

Mitochondria age differently depending upon whether they’re located in the liver, heart, or kidney, scientists find in flies and mice.

In mice, injected fragments of a naturally occurring protein boost memory in young and old animals and improve cognition and mobility in a model of neurodegenerative disease. 

While the epigenetic clock is a useful tool for research and has solid scientific backing, scientists say the product’s use to consumers is limited.