aging

Harvard biologist George Church talks gene therapy, aging, and reviving the woolly mammoth with Stephen Colbert.

Greenland sharks can live an estimated 400 years, beating the previous vertebrate longevity record, scientists report.

Mismatched ancestral origins of mitochondrial and nuclear DNA boost mouse health.

A biotech company reports that an experimental treatment elongated its CEO’s telomeres. 

Studies reach conflicting conclusions on GDF11 as a rejuvenating factor.

Scientists identify an inverse relationship between longevity in killifish and the expression of genes related to cellular respiration.

A drug commonly used in experiments on the model organism can skew the results of aging studies, researchers show.

A study on human cells reveals how cellular aging affects the 3-D architecture of chromosomes.

The removal of senescent cells in mice leads to an increased lifespan and later onset of age-linked diseases, scientists show.

Whether a critical circadian clock gene is deleted before or after birth impacts the observed aging-related effects in mice.

Signs of getting older are less common among rodents with ramped-up ghrelin production.

Overvaluing startups; undervaluing human research participants; curing aging?

As the rhythmic expression of many genes falls out of sync in older human brains, a subset of transcripts gain rhythmicity with age.

In 2015, The Scientist dove deep into the latest research on aging, HIV, hearing, and obesity.

The latest analysis on GDF11, a proposed antiaging protein, blames discrepancies in the literature on misreported doses and misinterpretation.

Google’s parent company is launching a research-and-development project as a standalone firm.

Aggregate-forming amyloid β proteins are replenished more slowly with age, and this may contribute to a person's risk of developing Alzheimer’s disease.

Calorie restriction in the organism extends lifespan, supporting a long-standing view that had been challenged by a study published last year.

And a diet that includes a few days of caloric restriction each month reduces biomarkers of aging and disease in people, according to a small trial.

Previously shown to boost muscle growth in aged mice, a protein’s role in regeneration just got more complicated.