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Cancer Immunotherapist

By | April 1, 2015

Scientist to Watch Yvonne Saenger explains recent advances in using biomarkers to identify cancer patients who might benefit most from immunotherapy.

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Cancer Kismet

By | April 1, 2015

Fate mapping allows researchers to follow cancer progression from its cell type of origin.

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Capsule Reviews

By | April 1, 2015

Junk DNA, Cuckoo, Sapiens, and Cool

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Control ALT, Delete Cancer

By , , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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Getting Your Sugar Fix

By | April 1, 2015

A guide to glycan microarrays

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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Through a Spider’s Eyes

By | April 1, 2015

Deciphering how a jumping spider sees the world and processes visual information may yield insights into long-standing robotics problems.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Yvonne Saenger: Immunotherapy Pioneer

Yvonne Saenger: Immunotherapy Pioneer

By | April 1, 2015

Assistant Professor, Department of Medicine, Columbia University. Age: 41

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