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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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image: Infographic: Circadian Clock Affects Health and Disease

Infographic: Circadian Clock Affects Health and Disease

By | April 1, 2017

The body's rhythms could affect numerous ailments as well as how people respond to treatments.

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image: Paralyzed Man Moves Arm with Neuroprosthetic

Paralyzed Man Moves Arm with Neuroprosthetic

By | March 30, 2017

Two chips implanted in a quadriplegic patient’s motor cortex and 36 electrodes in his right arm allow the man to control the movement of his right arm and hand.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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The University of Rhode Island neurotoxicologist and dean came to the U.S. for college in the 1980s. 

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image: Pathway to Polio Virulence Revealed

Pathway to Polio Virulence Revealed

By | March 23, 2017

Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.

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image: Image of the Day: Tubular Origins

Image of the Day: Tubular Origins

By | March 23, 2017

Murine neural tubes, with each image highlighting a different embryonic tissue type (blue). The neural tube itself (left) grows into the brain, spine, and nerves, while the mesoderm (middle) develops into other organs, and the ectoderm (right) forms skin, teeth, and hair.

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image: Consilience, Episode 2: In Tune

Consilience, Episode 2: In Tune

By | March 21, 2017

Ben Henry delves into the still-unanswered questions of where our musical preferences come from and what makes synesthetes tick.

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