Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.

Removing excess iron from aging mouse blood-forming cells enhances their regenerative capacity.

Edited by: Karen Young Kreeger T. Blunt, N.J. Finnie, G.E. Taccioli, G.C.M. Smith, J. Demengeot, T.M. Gottlieb, R. Mizuta, A.J. Varghese, F.W. Alt, P.A. Jeggo, S.P. Jackson, "Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine SCID mutation," Cell, 80:813-23, 1995. (Cited in almost 120 publications as of December 1996) Comments by Frederick W. Alt, Howard Hughes Medical Institute, Children's Hospital, Boston, and Harv

Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.

Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications. 

Scientists use virus-free gene therapy on patient-derived stem cells to repair spinal muscular atrophy in mice.

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

New details of the molecular process by which our cells consume themselves point to therapeutic potential.