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image: Toggling CRISPR Activity with a Chemical Switch

Toggling CRISPR Activity with a Chemical Switch

By | September 12, 2016

Researchers design a Cas9 enzyme that cuts DNA only in the presence of particular drug.

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image: Neonatal Gut Bacteria Might Promote Asthma

Neonatal Gut Bacteria Might Promote Asthma

By | September 12, 2016

Byproducts of gut microbes in some 1-month–old babies trigger inflammation that is linked to later asthma development, researchers find.

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image: Week in Review: September 5–9

Week in Review: September 5–9

By | September 9, 2016

Environmental magnetite in the human brain; prion structure takes shape; watching E. coli evolve in real time; learning from others’ behavior 

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Ancestries of nearly two dozen indigenous groups in the region reveal a close link between the genetic clustering of populations and the Kalahari Desert’s ecogeography.

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image: Zika Update

Zika Update

By | September 7, 2016

Virus’s genome to aid in diagnoses; bees caught in crossfire of mosquito sprays; Zika spreads in Asia; US Congress revisits Zika funding

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image: Designing In Vitro Models of the Blood-Brain Barrier

Designing In Vitro Models of the Blood-Brain Barrier

By | September 1, 2016

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

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image: Smart Skin Enables Magnetoreception

Smart Skin Enables Magnetoreception

By | September 1, 2016

Researchers develop a wearable technology that can detect magnetic fields and translate the signal into a visual display—a first step toward equipping humans with an entirely new sense.

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image: The Challenges of Rare-Disease Research

The Challenges of Rare-Disease Research

By | September 1, 2016

With few resources and hesitant investors, basic scientists must rely on clinicians, patient advocates, and their own keen eye for biological connections.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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