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image: Infographic: Proteasome Basics

Infographic: Proteasome Basics

By | May 1, 2017

The structure and function of the cell's protein-degrading machine

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image: Marching Into an Uncertain Future

Marching Into an Uncertain Future

By | April 20, 2017

Can professional organizations and societies parlay the groundswell of support culminating in this weekend’s March for Science into more-effective science advocacy?

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image: Report: Boost Funds for Basic Science in Canada

Report: Boost Funds for Basic Science in Canada

By | April 12, 2017

An independent review of Canadian science reveals a need for additional funds to investigator-led, basic research.

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image: Viral Trigger for Celiac Disease?

Viral Trigger for Celiac Disease?

By | April 6, 2017

A common, seemingly benign human virus can trigger an immune response that leads to celiac disease in a mouse model, researchers show. 

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Mice engineered to overproduce the organelles involved in cell division spontaneously develop malignancies.

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image: Gel Scaffolds for Delivery of Immunotherapies

Gel Scaffolds for Delivery of Immunotherapies

By | April 1, 2017

Using biocompatible polymers to carry cancer immune therapies directly to the tumor

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image: How Will Cancer Research Fare Under Trump?

How Will Cancer Research Fare Under Trump?

By | April 1, 2017

The new administration has not yet made its intentions clear.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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image: Starvation Response Triggers Melanoma Invasion

Starvation Response Triggers Melanoma Invasion

By | April 1, 2017

Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.

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