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tag rare diseases cell molecular biology microbiology genetics genomics
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Context Is Key: Unlocking Tissue Complexity with Spatial Biology
Deanna MacNeil, PhD
| Mar 13, 2023
| 4 min read
Scientists combine spatially resolved imaging analyses with cutting edge single cell techniques for greater insight into fundamental and disease relevant pathways.
Introduction to AAV Gene Therapies
Nicole Stivers, PhD
| Jun 29, 2023
| 4 min read
Small-scale successes in rare disease treatments prime large-scale industry innovations.
Single Cell Sequencing in a Nutshell
Niki Spahich, PhD
| Mar 31, 2023
| 4 min read
By exploring the inner workings of individual cells, rather than averaging bulk populations, researchers identify rare and important cell subtypes.
Redesigning Medicine Using Synthetic Biology
Alison Halliday, PhD,
Technology Networks
| Jun 21, 2023
| 5 min read
Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.
Capturing Heterogeneity: How Single Cell Analysis Reshapes Health and Disease Research
The Scientist
| Sep 30, 2021
| 1 min read
Timothy O’Sullivan and Jacob Blum will discuss how they use single cell data to understand complex biological systems.
EvaGreen
®
Dye: The Swiss Army Knife of qPCR
Biotium
| Mar 1, 2024
| 7 min read
A green fluorescent dye with a novel DNA binding mechanism improves signal-to-noise in different DNA amplification assays.
The Genetic Components of Rare Diseases
Kelly Rae Chi
| Jul 1, 2016
| 9 min read
Techniques for determining which genes or genetic variants are truly detrimental
Deficient RNA Editing Implicated in Inflammatory Disease
Alejandra Manjarrez, PhD
| Aug 5, 2022
| 3 min read
Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.
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