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tag brca1 disease medicine genetics genomics neuroscience

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
<h1 >Precision Medicine: A New Era in Cancer Therapy</h1>
Precision Medicine: A New Era in Cancer Therapy
Rebecca Roberts, PhD | Dec 15, 2023 | 6 min read
Precision medicine helps clinicians tailor individual treatments, addressing genetic mutations, tumor microenvironment variations, and therapeutic resistance.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
A silver tree showing roots and branches in a circle on a blue background.
Onward and Upward!
Kristie Nybo, PhD | Sep 8, 2023 | 9 min read
At The Scientist, we are strengthening our roots while reaching for the sky.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
A fishing cat with a fish in its mouth
Genome Spotlight: Fishing cat (Prionailurus viverrinus)
Christie Wilcox, PhD | Dec 22, 2022 | 5 min read
A high-quality reference genome for this vulnerable feline may help scientists understand why they’re so prone to transitional cell carcinoma in captivity.
Illuminated drawing of gastrointestinal tract overlayed on woman&rsquo;s hands and torso
“Gut Feeling” Takes on New Meaning
Iris Kulbatski, PhD | Jan 23, 2023 | 4 min read
Mechanically sensitive gut cells similar to touch sensors in the skin allow the intestine to feel and assess the physical properties of its contents.

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