A. J. S. Rayl | Feb 4, 2001 | 10+ min read
Researchers have suspected for years that chronic alcohol abuse and alcoholism change the programming of the human brain at the molecular level, particularly in the regions involving judgment and decision-making. In fact, during the past several decades, cell and animal studies have consistently indicated that changes in gene expression in the brain appear to be responsible for the tolerance, dependence, and neurotoxicity produced by chronic alcohol abuse.1 Until recently, however, technological