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» mutations and developmental biology

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image: A Tree  Takes Root

A Tree Takes Root

By | April 1, 2016

Four apparently unrelated individuals share a common ancestor from whom they inherited a rare mutation that predisposed them to the cancer they share.

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image: Guts and Glory

Guts and Glory

By | April 1, 2016

An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

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image: Pulling It All Together

Pulling It All Together

By | April 1, 2016

Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.

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image: Mutations Not Tied to Metastasis

Mutations Not Tied to Metastasis

By | February 25, 2016

Clinical cases link immune changes to a cancer’s spread through the body, but find no role for so-called “driver” mutations.

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image: Similar Data, Different Conclusions

Similar Data, Different Conclusions

By | February 23, 2016

By tweaking certain conditions of a long-running experiment on E. coli, scientists found that some bacteria could be prompted to express a mutant phenotype sooner, without the “generation of new genetic information.” The resulting debate—whether the data support evolutionary theory—is more about semantics than science.

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image: Adjustable Brain Cells

Adjustable Brain Cells

By | February 18, 2016

Neighboring neurons can manipulate astrocytes. 

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image: Domestication’s Downsides for Dogs

Domestication’s Downsides for Dogs

By | December 21, 2015

The selection of traits suitable for human companionship may have dragged along some unfavorable alleles.

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image: Cancer Not Just “Bad Luck”

Cancer Not Just “Bad Luck”

By | December 18, 2015

A new study refutes one published earlier this year that claimed random mutations were at the root of many tumors.

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image: One Gene, Two Disorders

One Gene, Two Disorders

By | December 11, 2015

Researchers link different mutations in a single gene to autistic and schizophrenic phenotypes in mice.

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image: The Cyclopes of Idaho, 1950s

The Cyclopes of Idaho, 1950s

By | December 1, 2015

A rash of deformed lambs eventually led to the creation of a cancer-fighting agent.

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