The Scientist

» mutations and developmental biology

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image: Embryo Watch

Embryo Watch

By | May 5, 2016

A new culture system allows researchers to track the development of human embryos in vitro for nearly two weeks. 

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image: Cellular Pruning Follows Adult Neurogenesis

Cellular Pruning Follows Adult Neurogenesis

By | May 2, 2016

Newly formed neurons in the adult mouse brain oversprout and get cut back.

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image: Advances in Genome Editing

Advances in Genome Editing

By | April 20, 2016

Researchers develop a CRISPR-based technique that efficiently corrects point mutations without cleaving DNA.

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image: Genetic Resilience

Genetic Resilience

By | April 11, 2016

An analysis of the genomes of nearly 600,000 healthy individuals reveals a handful of people who appear resistant to certain genetic disorders.

4 Comments

image: A Gut Feeling

A Gut Feeling

By | April 1, 2016

See profilee Hans Clevers discuss his work with stem cells and cancer in the small intestine.

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image: A Tree  Takes Root

A Tree Takes Root

By | April 1, 2016

Four apparently unrelated individuals share a common ancestor from whom they inherited a rare mutation that predisposed them to the cancer they share.

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image: Guts and Glory

Guts and Glory

By | April 1, 2016

An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

1 Comment

image: Pulling It All Together

Pulling It All Together

By | April 1, 2016

Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.

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image: Mutations Not Tied to Metastasis

Mutations Not Tied to Metastasis

By | February 25, 2016

Clinical cases link immune changes to a cancer’s spread through the body, but find no role for so-called “driver” mutations.

3 Comments

image: Similar Data, Different Conclusions

Similar Data, Different Conclusions

By | February 23, 2016

By tweaking certain conditions of a long-running experiment on E. coli, scientists found that some bacteria could be prompted to express a mutant phenotype sooner, without the “generation of new genetic information.” The resulting debate—whether the data support evolutionary theory—is more about semantics than science.

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