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image: Mutation vs. Mutation

Mutation vs. Mutation

By | November 3, 2016

Yeast study finds many instances—often among related genes—in which a mutation in one gene cancels the negative effects of a mutation in another.

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image: Largest Human Genetic Variation Repository Yet

Largest Human Genetic Variation Repository Yet

By | August 17, 2016

An open-access catalog of tens of thousands of human exome sequences highlights the power of a very large genomic dataset in pinpointing genes linked to rare diseases. 

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image: “Redhead” Gene Variant Boosts Melanoma Risk

“Redhead” Gene Variant Boosts Melanoma Risk

By | July 12, 2016

People without red hair who possess the variant are also more likely to develop this form of skin cancer, researchers report.

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image: Immune Defect Detected in Knockout Mice

Immune Defect Detected in Knockout Mice

By | May 20, 2016

Researchers have identified a mutation in a commonly used commercial mouse strain that could impact experimental results.

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image: Advances in Genome Editing

Advances in Genome Editing

By | April 20, 2016

Researchers develop a CRISPR-based technique that efficiently corrects point mutations without cleaving DNA.

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image: Genetic Resilience

Genetic Resilience

By | April 11, 2016

An analysis of the genomes of nearly 600,000 healthy individuals reveals a handful of people who appear resistant to certain genetic disorders.

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image: A Tree  Takes Root

A Tree Takes Root

By | April 1, 2016

Four apparently unrelated individuals share a common ancestor from whom they inherited a rare mutation that predisposed them to the cancer they share.

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image: Pulling It All Together

Pulling It All Together

By | April 1, 2016

Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.

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image: Mutations Not Tied to Metastasis

Mutations Not Tied to Metastasis

By | February 25, 2016

Clinical cases link immune changes to a cancer’s spread through the body, but find no role for so-called “driver” mutations.

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image: Similar Data, Different Conclusions

Similar Data, Different Conclusions

By | February 23, 2016

By tweaking certain conditions of a long-running experiment on E. coli, scientists found that some bacteria could be prompted to express a mutant phenotype sooner, without the “generation of new genetic information.” The resulting debate—whether the data support evolutionary theory—is more about semantics than science.

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